Author

L. A. Smith

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Assay:metagenomics· 1

Frequent Co-Authors

A. A. Fodor· 1 shared A. G. Lewis· 1 shared A. J. Pfeil· 1 shared E. C. Kennedy· 1 shared E. J. Murphy· 1 shared E. M. Glenny· 1 shared E. T. Rezeli· 1 shared F. Fouladi· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperCancer Biology

A. A. Fodor

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Regulation of inositol 5-phosphatase activity by the C2 domain of SHIP1 and SHIP2

W. J. Bradshaw, E. C. Kennedy, T. Moreira, L. A. Smith, R. Chalk, V. L. Katis, J. L. Benesch, P. E. Brennan, E. J. Murphy, O. Gileadi

The paper determines structures of SHIP1 and SHIP2 phosphatase and C2 domains, showing the C2 domain modulates phosphatase activity more in SHIP2 than SHIP1, providing insights for drug development.

bioRxiv · Jul 31, 2023Biochemistry

Calorie Restriction Outperforms Bariatric Surgery in a Murine Model of Obesity and Triple-Negative Breast Cancer

M. F. Coleman, K. K. Camp, T. L. McFarlane, S. S. Doerstling, S. A. Khatib, E. T. Rezeli, A. G. Lewis, A. J. Pfeil, L. A. Smith, F. Fouladi, W. Gong, E. M. Glenny, J. S. Parker, G. L. Milne, I. M. Carroll, , S. D. Hursting

This study compares the effects of bariatric surgery and calorie restriction on obesity-driven triple-negative breast cancer in mice, finding calorie restriction more effective in reversing tumor growth.

bioRxiv · May 19, 2023 · PreprintCancer Biology