Bioorthogonal labeling with tetrazine-dyes forsuper-resolution microscopy
G. Beliu, A. Kurz, A. Kuhlemann, L. Behringer-Pliess, N. Wolf, J. Seibel, Z.-D. Shi, M. Schnermann, J. Grimm, L. Lavis, S. Doose, M. Sauer
This study explores the use of tetrazine-dyes in super-resolution microscopy via Diels-Alder reactions with TCO-modified ncAAs, showing enhanced fluorescence and specific labeling capabilities.
bioRxiv · Dec 21, 2018Biochemistry