Cytosolic bacterial pathogens activate TLR pathways in tumors that synergistically enhance STING agonist cancer therapies
M. Danielson, C. J. Nicolai, T. T. Vo, N. Wolf, T. P. Burke
This study shows that combining STING and TLR agonists enhances anti-tumor effects in mice, with synergistic responses observed when using bacterial pathogens and small molecule TLR agonists.
bioRxiv · Jan 30, 2024Cancer Biology