Author

S. Doose

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biophysics· 2 Biochemistry· 1 Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Assay:fluorescence / live-cell microscopy· 4 Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Organism:human· 3 Approach:microscopy & imaging analysis· 3 Research Focus:imputation· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

M. Sauer· 5 shared A. Kuhlemann· 3 shared G. Beliu· 3 shared A. Ghosh· 2 shared D. A. Helmerich· 2 shared M. Meub· 2 shared A. Kurz· 1 shared C. Verbruggen· 1 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

5 shared papersBiophysics

M. Sauer

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Decoding the molecular interplay of endogenous CD20 and Rituximab with fast volumetric nanoscopy

M. Sauer, A. Ghosh, M. Meub, D. A. Helmerich, S. Doose, P. Eiring, K. M. Kortuem

The paper develops TDI-DNA-PAINT and LLS microscopy to study CD20-rituximab interactions in B cells, revealing oligomeric states and polarization effects.

bioRxiv · Oct 9, 2023 · PreprintBiophysics

CARs are organized in nanodomains in the plasma membrane of T cells that accumulate at tumor contact sites

C. Verbruggen, L. Gehrke, N. Banholzer, A. Ghosh, S. Reinhard, J. Weber, S. Doose, H. Einsele, M. Hudecek, T. Nerreter, M. Sauer

This study uses super-resolution microscopy to show CARs form nanodomains on T-cell membranes, accumulating at tumor sites, with transposon-engineered CARs showing higher density and faster anti-tumor activity.

bioRxiv · Jul 19, 2023 · PreprintImmunology

Sub-10 nm fluorescence imaging

M. Sauer, D. A. Helmerich, G. Beliu, D. Taban, M. Meub, A. Kuhlemann, S. Doose, M. Streit

This study identifies challenges in achieving sub-10 nm resolution in fluorescence imaging and proposes a method combining time-resolved detection and photoswitching fingerprint analysis to overcome these challenges.

bioRxiv · Feb 8, 2022 · PreprintBiophysics

Bioorthogonal labeling of transmembrane proteins with non-canonical amino acids allows access to masked epitopes in live neurons

D. Bessa-Neto, A. Kuhlemann, G. Beliu, V. Pecoraro, S. Doose, N. Retailleau, N. Chevrier, D. Perrais, M. Sauer, D. Choquet

The paper develops a method to label and image masked epitopes of transmembrane proteins in live neurons using non-canonical amino acids and genetic code expansion.

bioRxiv · Feb 27, 2021 · PreprintCell Biology

Bioorthogonal labeling with tetrazine-dyes forsuper-resolution microscopy

G. Beliu, A. Kurz, A. Kuhlemann, L. Behringer-Pliess, N. Wolf, J. Seibel, Z.-D. Shi, M. Schnermann, J. Grimm, L. Lavis, S. Doose, M. Sauer

This study explores the use of tetrazine-dyes in super-resolution microscopy via Diels-Alder reactions with TCO-modified ncAAs, showing enhanced fluorescence and specific labeling capabilities.

bioRxiv · Dec 21, 2018Biochemistry