Author

L. Bintu

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Assay:DNA methylation· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Approach:statistical model· 2 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1 Approach:experimental assay· 1

Frequent Co-Authors

A. Fanton· 1 shared A. R. Thurm· 1 shared A. S. Bhatt· 1 shared B. N. Archibald· 1 shared C. H. Ludwig· 1 shared D. Fang· 1 shared J. F. Nickels· 1 shared J. Schaepe· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBioengineering

A. Fanton

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Author profile →

2 papers

Recent·Most cited

The H3.3 K36M oncohistone disrupts the establishment of epigenetic memory through loss of DNA methylation

J. Sinha, J. F. Nickels, A. R. Thurm, C. H. Ludwig, B. N. Archibald, M. M. Hinks, J. Wan, D. Fang, L. Bintu

This study shows that H3.3K36M mutation reduces epigenetic memory and promoter methylation by disrupting the conversion of H3K9me3 domains into DNA methylation.

bioRxiv · Oct 13, 2023 · PreprintCell Biology

Large-scale discovery of recombinases for integrating DNA into the human genome

M. G. Durrant, A. Fanton, J. Tycko, M. Hinks, S. S. Chandrasekaran, N. T. Perry, J. Schaepe, P. P. Du, P. Lotfy, M. C. Bassik, L. Bintu, A. S. Bhatt, P. D. Hsu

This paper identifies and validates new large serine recombinases (LSRs) for efficient DNA integration into human genomes, achieving higher efficiency than existing tools.

bioRxiv · Nov 5, 2021Bioengineering