Author

L. Cano

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:statistical model· 1 Organism:virus· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

A. Castillo Morales· 1 shared A. M. Rice· 1 shared A. T. Ho· 1 shared B. Young· 1 shared C. Mordstein· 1 shared G. Kudla· 1 shared L. D. Hurst· 1 shared S. Mühlhausen· 1 shared

Activity by Year

2020-2020 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 36 mutual co-author links

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1 shared paperEvolutionary Biology

A. Castillo Morales

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1 paper

Recent·Most cited

Evidence for strong mutation bias towards, and selection against, T/U content in SARS-CoV2: implications for attenuated vaccine design.

A. M. Rice, A. Castillo Morales, A. T. Ho, C. Mordstein, S. Mühlhausen, S. Watson, L. Cano, B. Young, G. Kudla, L. D. Hurst

The paper analyzes SARS-CoV-2 mutation patterns to show strong T/U mutation bias and selection against T, suggesting a strategy for vaccine attenuation by increasing usage of common synonymous codons.

bioRxiv · May 11, 2020 · PreprintEvolutionary Biology