TRPV4 inhibition prevents increased water diffusion and blood-retina barrier breakdown in the retina of streptozotocin-induced diabetic mice.
s. thebault, M. Orduna Rios, R. Noguez Imm, N. M. Hernandez Godinez, A. M. Bautista Cortes, W. Liedtke, A. Martinez Torres, L. Concha
This study shows TRPV4 inhibition reduces water diffusion and blood-retina barrier breakdown in diabetic mice retinas but does not fully reverse these effects.
bioRxiv · Jan 30, 2019Physiology