Author

W. Liedtke

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Physiology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 2 Organism:human· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:electrophysiology· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Y. Chen· 2 shared A. M. Bautista Cortes· 1 shared A. Martinez Torres· 1 shared C. Moore· 1 shared G. Moon· 1 shared H. Yang· 1 shared J. Zhang· 1 shared K. Z. Shan· 1 shared

Activity by Year

2019-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersPhysiology

Y. Chen

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3 papers

Recent·Most cited

Functional coupling between TRPV4 channel and TMEM16F modulates human trophoblast fusion

Y. Zhang, P. Liang, K. Z. Shan, L. Feng, Y. Chen, W. Liedtke, H. Yang

The paper shows TRPV4 activates TMEM16F in trophoblasts, promoting cell fusion, and identifies this as a mechanism for syncytialization and disease-related fusion.

bioRxiv · Dec 11, 2021Physiology

Epidermal TRPV4 ion channels regulate UVB induced sunburn by triggering inflammmasome activation and MAPK signaling

C. Moore, S. Choi, G. Moon, J. Zhang, Y. Chen, W. Liedtke

This study investigates how TRPV4 ion channels in keratinocytes mediate UVB-induced inflammation by activating inflammasomes and MAPK signaling, leading to IL-1β secretion and pain.

bioRxiv · Jan 9, 2021 · PreprintPhysiology

TRPV4 inhibition prevents increased water diffusion and blood-retina barrier breakdown in the retina of streptozotocin-induced diabetic mice.

s. thebault, M. Orduna Rios, R. Noguez Imm, N. M. Hernandez Godinez, A. M. Bautista Cortes, W. Liedtke, A. Martinez Torres, L. Concha

This study shows TRPV4 inhibition reduces water diffusion and blood-retina barrier breakdown in diabetic mice retinas but does not fully reverse these effects.

bioRxiv · Jan 30, 2019Physiology