Author

L. Cottone

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Cancer Biology· 1

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

A. E. Grigoriadis· 1 shared A. M. Flanagan· 1 shared A. P. Leite· 1 shared C. Davies· 1 shared F. Amary· 1 shared H. J. Knowles· 1 shared H.-M. Lee· 1 shared J. Herrero· 1 shared

Activity by Year

2021-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

A. E. Grigoriadis

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1 paper

Recent·Most cited

Aberrant paracrine signalling for bone remodelling underlies the mutant histone-driven giant cell tumour of bone.

L. Cottone, L. Ligammari, H. J. Knowles, H.-M. Lee, S. Henderson, S. Bianco, C. Davies, S. Strauss, F. Amary, A. P. Leite, R. Tirabosco, K. Haendler, J. L. Schultze, J. Herrero, P. ODonnell, , A. M. Flanagan

This study identifies aberrant paracrine signaling between osteoprogenitors and osteoclasts driven by H3.3 mutations as a mechanism underlying giant cell tumor of bone and its response to treatment.

bioRxiv · Dec 27, 2021Cancer Biology