Cancer BiologyJournal of Translational MedicinePeer-reviewed
A Community Challenge to Predict Clinical Outcomes After Immune Checkpoint Blockade in Non-Small Cell Lung Cancer
M. Mason, O. Lapuente-Santana, A. S. Halkola…·B. G. Vincent
The paper evaluates predictive models for immune checkpoint inhibitor outcomes in NSCLC using clinical trial data from two RCTs, finding that models combining PD-L1, TMB, and immune signatures outperform single biomarkers.
DOI 10.1186/s12967-023-04705-3