Integrated AlphaFold2 and DEER investigation of the conformational dynamics of a pH-dependent APC antiporter
D. del Alamo, L. DeSousa, R. M. Nair, S. Rahman, J. Meiler, H. Mchaourab
This paper investigates the conformational dynamics of the pH-dependent APC antiporter GadC using DEER spectroscopy and AlphaFold2 models, revealing acid-induced structural changes and substrate-specific dynamics.
bioRxiv · Apr 13, 2022 · PreprintBiophysics