Author

L. Digilio

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cell Biology· 3

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell signaling & trafficking· 3 Approach:experimental assay· 3 Assay:proteomics· 3 Research Focus:cell type annotation· 2 Organism:human· 2 Organism:mouse· 2 Approach:biophysical modeling· 1 Research Focus:differential expression· 1

Frequent Co-Authors

B. Winckler· 3 shared C. C. Yap· 3 shared D. A. Garcia· 1 shared L. McMahon· 1 shared M. M. Magaj· 1 shared R. J. Mulligan· 1 shared S. Redemann· 1 shared

Activity by Year

2017-2023 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 15 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersCell Biology

B. Winckler

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Collapse of late endosomal pH elicits a rapid Rab7 response via V-ATPase and RILP.

R. J. Mulligan, M. M. Magaj, L. Digilio, S. Redemann, C. C. Yap, B. Winckler

The paper shows that neutralizing late endosomal pH via LLOMe or NH4Cl hyper-activates Rab7 through V-ATPase and RILP, disrupting tubulation and CI-M6PR trafficking.

bioRxiv · Oct 24, 2023Cell Biology

Validation of species-specificity of two commercial antibodies directed against RILP (Rab-interacting lyosomal protein).

C. C. Yap, L. Digilio, B. Winckler

The paper validates two commercial anti-RILP antibodies, finding they only recognize human RILP and show differential behavior in neurons versus HEK293 cells.

bioRxiv · Nov 1, 2022 · PreprintCell Biology

Bulk degradation of dendritic cargos requires Rab7-dependent transport in Rab7-positive/LAMP1-negative endosomes to somatic lysosomes.

C. C. Yap, L. Digilio, L. McMahon, D. A. Garcia, B. Winckler

bioRxiv · Nov 8, 2017Cell Biology