Author

R. J. Mulligan

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Cell Biology· 1

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Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:imaging· 1 Assay:proteomics· 1

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B. Winckler· 1 shared C. C. Yap· 1 shared L. Digilio· 1 shared M. M. Magaj· 1 shared S. Redemann· 1 shared

Activity by Year

2023-2023 · peak 1/yr

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1 shared paperCell Biology

B. Winckler

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1 paper

Recent·Most cited

Cell BiologybioRxivOct 24, 2023

Collapse of late endosomal pH elicits a rapid Rab7 response via V-ATPase and RILP.

R. J. Mulligan, M. M. Magaj, L. Digilio…·B. Winckler

The paper shows that neutralizing late endosomal pH via LLOMe or NH4Cl hyper-activates Rab7 through V-ATPase and RILP, disrupting tubulation and CI-M6PR trafficking.

DOI 10.1242/jcs.261765

humanproteomics

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