Author

C. C. Yap

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 4

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 4 Approach:experimental assay· 4 Assay:proteomics· 4 Organism:mouse· 3 Research Focus:cell type annotation· 2 Organism:human· 2 Approach:biophysical modeling· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

B. Winckler· 4 shared L. Digilio· 3 shared C. J. Bott· 1 shared D. A. Garcia· 1 shared J. Keil· 1 shared K. Kwan· 1 shared L. McMahon· 1 shared L. P. McMahon· 1 shared

Activity by Year

2017-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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4 shared papersCell Biology

B. Winckler

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Author profile →

4 papers

Recent·Most cited

Cell BiologybioRxivOct 24, 2023

Collapse of late endosomal pH elicits a rapid Rab7 response via V-ATPase and RILP.

R. J. Mulligan, M. M. Magaj, L. Digilio…·B. Winckler

The paper shows that neutralizing late endosomal pH via LLOMe or NH4Cl hyper-activates Rab7 through V-ATPase and RILP, disrupting tubulation and CI-M6PR trafficking.

DOI 10.1242/jcs.261765

humanproteomics

𝕏 PostBluesky

Cell BiologybioRxivPreprintNov 1, 2022

Validation of species-specificity of two commercial antibodies directed against RILP (Rab-interacting lyosomal protein).

C. C. Yap, L. Digilio, B. Winckler

The paper validates two commercial anti-RILP antibodies, finding they only recognize human RILP and show differential behavior in neurons versus HEK293 cells.

DOI 10.1101/2022.11.01.514750

humanmouse

𝕏 PostBluesky

Cell BiologybioRxivMar 10, 2020

Nestin selectively facilitates the phosphorylation of the Lissencephaly-linked protein doublecortin (DCX) by cdk5/p35 to regulate growth cone morphology and Sema3a sensitivity in developing neurons

C. J. Bott, L. P. McMahon, J. Keil…·B. Winckler

DOI 10.1523/jneurosci.2471-19.2020

mouseproteomics

𝕏 PostBluesky

Cell BiologybioRxivNov 8, 2017

Bulk degradation of dendritic cargos requires Rab7-dependent transport in Rab7-positive/LAMP1-negative endosomes to somatic lysosomes.

C. C. Yap, L. Digilio, L. McMahon…·B. Winckler

DOI 10.1083/jcb.201711039

mouseproteomics

𝕏 PostBluesky