Phosphorylation by Aurora B kinase regulates caspase-2 activity and function
S. Kumar, Y. Lim, D. De Bellis, J. J. Sandow, L. Capalbo, P. P. D'Avino, J. M. Murphy, A. I. Webb, L. Dorstyn
This study identifies Aurora B kinase-mediated phosphorylation of caspase-2 at S384, which inhibits its catalytic activity and apoptosis function during mitotic catastrophe.
bioRxiv · Mar 5, 2020Cell Biology