L. E. Bertassoni

Perivascular cells function as mechano-structural sensors of vascular capillaries

This study shows perivascular cells sense mechanical changes in collagen matrix, affecting vascular function and contributing to fibrotic conditions.

A Single-Cell Bioprinting Method to Reconstruct Native Cellular Microenvironments with Subcellular Resolution

This paper introduces a single-cell bioprinting method that reconstructs native cellular microenvironments with subcellular resolution, enabling precise interrogation of spatial interactions.

In vitro development and optimization of cell-laden injectable bioprinted gelatin methacryloyl (GelMA) microgels mineralized on the nanoscale

This study develops and optimizes injectable bioprinted GelMA microgels that can be mineralized at the nanoscale to enhance osteocyte maturation and mimic bone microarchitecture.

Vascular inflammation exposes perivascular cells to SARS-CoV-2 infection

The paper tests if inflamed vessels expose perivascular cells to SARS-CoV-2 by showing increased spike protein binding in engineered capillaries under inflammatory conditions.

Effects of Controlled Dual Growth Factor Delivery on Bone Regeneration Following Composite Bone-Muscle Injury

This study evaluates a smart delivery system for dual growth factor (BMP-2 and VEGF) release in composite bone-muscle injuries, finding no synergistic effect but improved bone healing with low-dose delivery.

BoneMA - Synthesis and Characterization of a Methacrylated Bone-derived Hydrogel for Bioprinting of Vascularized Tissues

This study synthesizes and characterizes a methacrylated bone-derived hydrogel (BoneMA) for bioprinting vascularized tissues, showing its cytocompatibility and ability to form vascular networks.

3D printing of Microgel-loaded Modular LEGO-like Cages as Instructive Scaffolds for Tissue Engineering

This paper introduces a 3D-printed modular LEGO-like cage scaffold system for tissue engineering that allows scalable assembly and controlled therapeutic loading.

The tooth on-a-chip: a microphysiologic model system mimicking the pulp-dentin interface and its interaction with biomaterials

The paper develops a tooth-on-a-chip model to study dental pulp cell responses to biomaterials, finding that HEMA > SB > PA are cytotoxic and cells show higher metabolic activity on-chip than off-chip.