Author

L. Egli

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:drug response / drug discovery· 1 Assay:flow cytometry· 1 Assay:proteomics· 1

Frequent Co-Authors

J. Mietz· 2 shared A. Holtermann· 1 shared C. Munz· 1 shared C. Schultheiss· 1 shared D. Anz· 1 shared E. Riva· 1 shared F. Maerkl· 1 shared G. Boero· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersImmunology

J. Mietz

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Human effector CD8+ T cells with an exhausted-like phenotype control tumor growth in vivo in a humanized tumor model

J. Mietz, M. Kaulfuss, L. Egli, L. Opitz, C. Munz, O. Chijioke

This study establishes an immunocompetent humanized tumor model and identifies exhausted-like CD8+ T cells with antitumor activity in vivo.

bioRxiv · Oct 11, 2023 · PreprintImmunology

Mutation-specific CAR T cells as precision therapy for IGLV3-21R110 expressing high-risk chronic lymphocytic leukemia

F. Maerkl, C. Schultheiss, M. Ali, S.-S. Chen, L. Egli, J. Mietz, O. Chijoke, L. Paschold, S. Spajic, A. Holtermann, J. Doerr, S. Stock, I. Piseddu, D. Anz, M. Duehren-von Minden, , M. Binder

This study develops CAR T cells targeting a specific mutation in CLL to selectively kill cancer cells while sparing healthy B cells.

bioRxiv · Sep 29, 2023 · PreprintCancer Biology

NMR microsystem for label-free characterization of 3D nanoliter microtissues

M. Grisi, G. M. Conley, K. J. Rodriguez, E. Riva, L. Egli, W. Moritz, J. Lichtenberg, J. Brugger, G. Boero

The paper introduces an NMR microsystem for non-invasive chemical analysis of 3D microtissues at the nanoliter scale, demonstrating its application to model lipid metabolism in NAFLD.

bioRxiv · Apr 26, 2020Bioengineering