Real Time PCR for the Evaluation of Treatment Response in Clinical Trials of Adult Chronic Chagas Disease: Usefulness of Serial Blood Sampling and qPCR Replicates.
R. Parrado, J. C. Ramirez, A. de la Barra, C. Alonso-Vega, N. A. Juiz, L. Ortiz, D. Illanes, F. Torrico, J. Gascon, F. Alves, L. Flevaud, L. Garcia, A. G. Schijman, I. Ribeiro
This paper evaluates serial blood sampling and qPCR replicates to improve PCR sensitivity for detecting treatment response in Chagas disease trials.
bioRxiv · Jun 11, 2018Microbiology