Author

L. Franchi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Assay:metabolomics· 1 Approach:statistical model· 1

Frequent Co-Authors

B. Magnuson· 2 shared C. A. Lyssiotis· 2 shared H. Hong· 2 shared L. Zhang· 2 shared M. Shan· 2 shared N. Mbah· 2 shared P. Sajjakulnukit· 2 shared A. Andren· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

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2 shared papersCancer Biology

B. Magnuson

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Therapeutic targeting of differentiation state-dependent metabolic vulnerabilities in DIPG

N. Mbah, A. Myers, C. Chung, J. Thompson, H. Hong, P. Sajjakulnukit, Z. Nwosu, M. Shan, S. Sweha, D. Maydan, B. Chen, L. Zhang, B. Magnuson, Z. Zui, D. Wahl, , C. A. Lyssiotis

This study identifies metabolic vulnerabilities in DIPG subtypes and shows that targeting these vulnerabilities with specific drugs can extend survival in preclinical models.

bioRxiv · Mar 1, 2022 · PreprintCancer Biology

OXPHOS Promotes Apoptotic Resistance and Persistence in TH17 cells

H. Hong, N. Mbah, M. Shan, K. Loesel, L. Lin, P. Sajjakulnukit, A. Andren, A. Hayashi, B. Magnuson, Z. Li, Y. Xie, L. Zhang, Y. L. Lei, A. Opipari, R. J. Arguello, , C. A. Lyssiotis

This study shows that OXPHOS enhances TH17 cell survival and persistence by promoting mitochondrial fitness and anti-apoptotic markers.

bioRxiv · Oct 1, 2021 · PreprintImmunology