Author

L. Frazier

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:virus· 2 Assay:proteomics· 1

Frequent Co-Authors

B. Lubinski· 2 shared G. Whittaker· 2 shared J. A. Jaimes· 2 shared S. Daniel· 2 shared T. Tang· 2 shared D. Bugumbe· 1 shared D. Diel· 1 shared J. L. Cunningham· 1 shared

Activity by Year

2021-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersMicrobiology

B. Lubinski

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2 papers

Recent·Most cited

Spike protein cleavage-activation mediated by the SARS-CoV-2 P681R mutation: a case-study from its first appearance in variant of interest (VOI) A.23.1 identified in Uganda

B. Lubinski, L. Frazier, M. Phan, D. Bugumbe, J. L. Cunningham, T. Tang, S. Daniel, M. Cotten, J. A. Jaimes, G. Whittaker

The paper analyzes the P681R mutation in the SARS-CoV-2 spike protein of variant A.23.1, showing increased furin cleavage and infectivity compared to earlier variants, but only when combined with other spike changes.

bioRxiv · Jun 30, 2021 · PreprintMicrobiology

Functional evaluation of the P681H mutation on the proteolytic activation the SARS-CoV-2 variant B.1.1.7 (Alpha) spike

B. Lubinski, M. H. Fernandes, L. Frazier, T. Tang, S. Daniel, D. Diel, J. A. Jaimes, G. Whittaker

This study evaluates the impact of the P681H mutation in the SARS-CoV-2 B.1.1.7 spike on furin cleavage and viral entry, finding no significant effect on these processes.

bioRxiv · Apr 6, 2021Microbiology