T. Tang

Microbial Community Structure of an Anaerobic Side-stream Coupled Anoxic-aerobic Membrane Bioreactor (AOMBR-ASSR) for an In-situ Sludge Reduction Process

This study compares microbial community structures in two wastewater treatment processes, finding increased diversity and specific taxa in the anaerobic side-stream reactor that contribute to sludge reduction and nutrient removal.

Short-chain carboxylates facilitate the counting of yeasts in Sub-high temperature Daqu.

This study investigates the use of short-chain carboxylates to selectively inhibit mold growth in Sub-high temperature Daqu, improving yeast counting efficiency.

Isolation and electrochemical analysis of a facultative anaerobic electrogenic strain Klebsiella sp. SQ-1

The paper isolates a facultative anaerobic electrogenic strain Klebsiella sp. SQ-1 and demonstrates its high current density and power density in microbial fuel cells.

Identification of resistance mechanisms to small-molecule inhibition of TEAD-regulated transcription

This study identifies resistance mechanisms to TEAD inhibitors by showing MAPK hyperactivation can counteract their effects and suggests combining TEAD and MEK inhibition as a therapeutic strategy.

An Integrated Platform for in vivo Electrophysiology in Spatial Cognition Experiments

The paper introduces a flexible, cost-effective behavioral platform for spatial cognition research with software tools for precise neural event timing and reward delivery.

The glucocorticoid dexamethasone impairs the expression of anti-viral mediators in activated macrophages by inhibiting both expression and function of interferon beta.

This study shows dexamethasone inhibits antiviral gene expression in macrophages by suppressing IFNβ expression and downstream interferon-regulated genes.

Comparison between Canine and Porcine Models of Chronic Deep Venous Thrombosis

This study induces chronic deep venous thrombosis in canine and porcine models and compares their suitability for translational therapeutic research.

Characterizing Mineral Ellipsoids in New Bone Formation at the Interface of Ti6Al4V Porous Implants

This paper characterizes mineral ellipsoid packing at the bone-implant interface of Ti6Al4V porous implants using microscopy techniques and identifies orientation shifts that may contribute to bone strengthening.

Cortico-Striatal Beta-Oscillations as a Marker of Learned Reward Value

The paper identifies beta-oscillations in cortico-striatal regions as markers of learned reward value across multiple behavioral tasks in rats.

Transgene by Germplasm Interactions Can Impact Transgene Evaluation

This study evaluates how genetic background affects transgene performance in maize, finding variable yield impacts across different hybrid combinations.

Methods for Evaluating Effects of Transgenes for Quantitative Traits

This study evaluates three methods for estimating transgene effects across genetic backgrounds and environments, finding that bulked F3 lines topcrossed to a tester inbred provide the most effective approach.

Tree species and genetic diversity increase productivity via functional diversity and trophic feedbacks

This study shows that both tree species and genetic diversity increase productivity through functional diversity and trophic feedbacks, with genetic diversity effects varying between monocultures and mixtures.

A mechanistic understanding of the modes of Ca2+ ion binding to the SARS-CoV-1 fusion peptide and their role in the dynamics of host membrane penetration

This study identifies specific Ca2+ binding residue pairs in SARS-CoV-1 fusion peptide that promote or inhibit membrane insertion through molecular dynamics and biological assays.

Inhibitors of L-type calcium channels show therapeutic potential for treating SARS-CoV-2 infections by preventing virus entry and spread

This study tests L-type calcium channel blockers for inhibiting SARS-CoV-2 infection in cell culture, finding that felodipine and nifedipine limit virus entry and infection with minimal toxicity.

ADAR mediated A-to-I RNA editing affects SARS-CoV-2 characteristics and fuels its evolution

The paper identifies A-to-I RNA editing in SARS-CoV-2 by analyzing RNA-seq data and shows it affects viral characteristics and evolution.

Spike protein cleavage-activation mediated by the SARS-CoV-2 P681R mutation: a case-study from its first appearance in variant of interest (VOI) A.23.1 identified in Uganda

The paper analyzes the P681R mutation in the SARS-CoV-2 spike protein of variant A.23.1, showing increased furin cleavage and infectivity compared to earlier variants, but only when combined with other spike changes.

Atmospheric plasma jet device for versatile electron microscope grid treatment

This paper introduces a non-thermal atmospheric plasma jet system for treating electron microscope grids, enabling hydrophilic surface modification without vacuum requirements.

Perfecting and extending the near-infrared biological window

The paper defines and extends the near-infrared biological window for improved in vivo fluorescence imaging, proposing new regions and demonstrating enhanced imaging capabilities.

Functional evaluation of the P681H mutation on the proteolytic activation the SARS-CoV-2 variant B.1.1.7 (Alpha) spike

This study evaluates the impact of the P681H mutation in the SARS-CoV-2 B.1.1.7 spike on furin cleavage and viral entry, finding no significant effect on these processes.

Targeting properdin - Structure and function of a novel family of tick-derived complement inhibitors

This study identifies and characterizes a novel family of tick-derived complement inhibitors, CirpA, which bind to properdin and inhibit complement activation.

Weak effect of Gypsy retrotransposon bursts on Sonneratia alba salt stress gene expression

This study examines the impact of Gypsy retrotransposon bursts on gene expression in Sonneratia alba under salt stress, finding limited correlation between TE activity and nearby gene expression.

Meeting experiments at the diffraction barrier: an in-silico widefield fluorescence microscopy

This paper introduces an in-silico widefield fluorescence microscopy technique that generates synthetic images from molecular simulations to enable cross-validation with experimental data.

Can we harness digital technologies and physiology to hasten genetic gain in U.S. maize breeding?

This study uses digital technologies and physiology to improve genetic gain in maize breeding by enhancing predictive models and breeding objectives.

Extracellular vesicles mediate the intercellular exchange of nanoparticles

This study investigates how nanoparticles exchange between cells, showing that extracellular vesicles significantly facilitate this process.

iRGD-liposomes enhance tumor delivery and therapeutic efficacy of antisense oligonucleotide drugs against primary prostate cancer and bone metastasis

This paper demonstrates that iRGD-liposomes enhance the delivery and efficacy of AR-ASO in treating prostate cancer and bone metastasis without increasing toxicity.

Two decades of creating drought tolerant maize and underpinning prediction technologies in the US corn-belt: Review and perspectives on the future of crop design

This paper reviews drought tolerant maize breeding efforts and shows increased crop improvement rates, suggesting future crop design through integrated prediction technologies.

Proteolytic activation of SARS-CoV-2 spike at the S1/S2 boundary: potential role of proteases beyond furin

This study investigates the role of S1/S2 cleavage in SARS-CoV-2 spike protein activation, showing its necessity for early pathway entry in Calu-3 cells and involvement of proteases beyond furin.

Reproductive resilience but not root architecture underpin yield improvement in maize

This study shows that yield improvement in maize is driven by reproductive resilience rather than changes in root architecture or water capture.

Ca2+ ions promote fusion of Middle East Respiratory Syndrome coronavirus with host cells and increase infectivity

This study shows that Ca2+ ions enhance MERS-CoV fusion and infectivity by interacting with specific residues in the spike protein's fusion peptide.

Run or die in the evolution of new microRNAs - Testing the Red Queen hypothesis on de novo new genes

The paper tests the Red Queen hypothesis by analyzing two Drosophila de novo miRNAs, finding their fitness contributions vary between species, supporting their different evolutionary fates.