Author

L. Graetz

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pharmacology & Toxicology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Assay:proteomics· 2 Approach:biophysical modeling· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

G. Schulte· 2 shared P. Kozielewicz· 2 shared C.-F. Bowin· 1 shared G. Davidson· 1 shared H. Schihada· 1 shared J. J. Sajkowska-Kozielewicz· 1 shared J. Wesslowski· 1 shared K. Petzold· 1 shared

Activity by Year

2022-2022 · peak 2/yr

Co-Author Collaboration Network

9 top collaborators · 24 mutual co-author links

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2 shared papersPharmacology & Toxicology

G. Schulte

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2 papers

Recent·Most cited

WNT stimulation induced conformational dynamics in the Frizzled-Dishevelled interaction

C.-F. Bowin, P. Kozielewicz, L. Graetz, M. Kowalski-Jahn, H. Schihada, G. Schulte

The paper analyzes the FZD5-DVL2 interaction to uncover WNT-induced conformational dynamics in a ternary complex.

bioRxiv · Jul 19, 2022 · PreprintPharmacology & Toxicology

Receptor levels determine binding affinity of WNT-3A to Frizzled 7 in a colorectal cancer model

L. Graetz, J. J. Sajkowska-Kozielewicz, J. Wesslowski, K. Petzold, G. Davidson, G. Schulte, P. Kozielewicz

The paper assesses WNT-3A binding affinity to endogenous versus overexpressed FZD7 in colorectal cancer cells and finds lower affinity with higher receptor concentrations.

bioRxiv · Jul 4, 2022Pharmacology & Toxicology