Author

L. Grontved

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Organism:human· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

M. Carretta· 2 shared A. Kalvisa· 1 shared A. M. Askehoj Romer· 1 shared A. M. Carnaz Simoes· 1 shared A. M. Hvid Larsen· 1 shared A. Roslind· 1 shared A. Zedlitz Johansen· 1 shared D. E. Kuczek· 1 shared

Activity by Year

2018-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersCancer Biology

M. Carretta

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Propranolol reduces sarcoma growth and enhances the response to anti-CTLA4 therapy by modulating the tumor microenvironment

K. Y. Fjaestad, A. M. Askehoj Romer, V. Goitea, A. Zedlitz Johansen, M.-L. Thorseth, M. Carretta, L. Henning Engelholm, L. Grontved, N. Junker, D. Hargbol Madsen

This study shows propranolol reduces sarcoma growth and enhances anti-CTLA4 therapy by modulating the tumor microenvironment through reduced angiogenesis and increased T cell infiltration.

bioRxiv · Mar 11, 2021 · PreprintCancer Biology

Collagen density regulates the activity of tumor-infiltrating T cells

D. E. Kuczek, A. M. Hvid Larsen, M. Carretta, A. Kalvisa, M. S. Siersbaek, A. M. Carnaz Simoes, A. Roslind, L. H. Engelholm, M. Donia, I. M. Svane, P. t. Straten, L. Grontved, D. H. Madsen

This study shows that high collagen density in tumors reduces T cell proliferation and cytotoxicity, while increasing regulatory T cells, suggesting collagen density modulates T cell function in the tumor microenvironment.

bioRxiv · Dec 12, 2018Immunology