Author

M. Donia

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 3 Organism:human· 3 Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Assay:clinical cohort / trial· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

I. M. Svane· 2 shared A. Draghi· 1 shared A. Gokuldass· 1 shared A. Kalvisa· 1 shared A. M. Carnaz Simoes· 1 shared A. M. Hvid Larsen· 1 shared A. Roslind· 1 shared A. Voros· 1 shared

Activity by Year

2018-2018 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersImmunology

I. M. Svane

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Collagen density regulates the activity of tumor-infiltrating T cells

D. E. Kuczek, A. M. Hvid Larsen, M. Carretta, A. Kalvisa, M. S. Siersbaek, A. M. Carnaz Simoes, A. Roslind, L. H. Engelholm, M. Donia, I. M. Svane, P. t. Straten, L. Grontved, D. H. Madsen

This study shows that high collagen density in tumors reduces T cell proliferation and cytotoxicity, while increasing regulatory T cells, suggesting collagen density modulates T cell function in the tumor microenvironment.

bioRxiv · Dec 12, 2018Immunology

Influence of mutagenic versus non-mutagenic pre-operative chemotherapy on the immune infiltration of breast cancer

A.-M. Tokes, O. Rusz, G. Cserni, E. Toth, G. Rubovszky, T. Tokes, L. Vizkeleti, L. Reiniger, R. Koszo, Z. Kahan, J. Kulka, M. Donia, A. Voros, Z. Szallasi

This study examines how mutagenic and non-mutagenic pre-operative chemotherapy affects immune infiltration in breast cancer, finding that increased stromal tumor-infiltrating lymphocytes (StrTIL) correlates with better distant metastasis-free survival in HR-negative cases.

bioRxiv · Oct 29, 2018Cancer Biology

Differential effects of corticosteroids and anti-TNF on tumor-specific immune responses - implications for the management of irAEs

A. Draghi, T. H. Borch, H. D. Radic, C. A. Chamberlain, A. Gokuldass, I. M. Svane, M. Donia

This study compares the effects of corticosteroids and anti-TNF on tumor-specific TILs in vitro, finding that corticosteroids significantly impair TIL activity while anti-TNF has a minor effect.

bioRxiv · Oct 8, 2018Cancer Biology