Sodium-myo-inositol cotransporter-1, SMIT1, promotes cardiac hypertrophy and fibrosis induced by pressure overload in mice
A. Marino, J. Cumps, L. Guilbert, A. Geiser, C. Baufays, A. Ginion, L. Ferte, S. Battault, F. De Matos, J. Ambroise, C. J. Zuurbier, F. Lezoualc'h, C. Pestiaux, G. Pyka, G. Kerckhofs, , C. Beauloye
This study shows that SMIT1 promotes cardiac hypertrophy and fibrosis in mice under pressure overload by enhancing IP3/Ca2+-dependent signaling pathways.
bioRxiv · Oct 25, 2023Cell Biology