Author

L. Hacker

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 4 Biophysics· 1

Signature Assays, Organisms & Methods

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Assay:imaging· 5 Organism:mouse· 4 Research Focus:cell type annotation· 2 Research Focus:clustering· 2 Approach:deep learning· 2 Approach:experimental assay· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1

Frequent Co-Authors

E. L. Brown· 3 shared J. Gröhl· 3 shared P. W. Sweeney· 3 shared S. E. Bohndiek· 3 shared T. L. Lefebvre· 3 shared S. Bohndiek· 2 shared B. Stolz· 1 shared E. St John Smith· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersBioengineering

E. L. Brown

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Author profile →

5 papers

Recent·Most cited

The effects of skin tone on photoacoustic imaging and oximetry

T. R. Else, L. Hacker, J. Gröhl, E. V. Bunce, R. Tao, S. Bohndiek

This study examines how skin melanin pigmentation affects photoacoustic imaging and oximetry, finding overestimation of blood oxygen saturation in higher Fitzpatrick skin types.

bioRxiv · Aug 17, 2023Bioengineering

Unsupervised segmentation of 3D microvascular photoacoustic images using deep generative learning

P. W. Sweeney, L. Hacker, T. L. Lefebvre, E. L. Brown, J. Gröhl, S. E. Bohndiek

This paper introduces an unsupervised deep learning model for segmenting 3D vascular networks from photoacoustic images without requiring manual labels.

bioRxiv · Apr 30, 2023Biophysics

Performance evaluation of mesoscopic photoacoustic imaging

L. Hacker, E. L. Brown, T. L. Lefebvre, P. W. Sweeney, S. E. Bohndiek

This study evaluates the performance of a commercial photoacoustic mesoscopy system, showing high precision with low coefficients of variation but highlighting challenges in imaging vessel-like structures.

bioRxiv · Oct 17, 2022Bioengineering

Quantification of vascular networks in photoacoustic mesoscopy

E. L. Brown, T. L. Lefebvre, P. W. Sweeney, B. Stolz, J. Gröhl, L. Hacker, Z. Huang, H. Harrington, H. Byrne, S. E. Bohndiek

This paper develops a framework to quantify 3D vascular networks using mesoscopic photoacoustic imaging and evaluates segmentation methods for accuracy.

bioRxiv · Nov 22, 2021Bioengineering

Photoacoustics resolves species-specific differences in haemoglobin concentration and oxygenation

L. Hacker, J. Brunker, E. St John Smith, I. Quiros-Gonzalez, S. Bohndiek

This study uses photoacoustic imaging to correlate in vitro blood biomarkers with species-specific haemoglobin concentration and oxygenation differences.

bioRxiv · Jun 23, 2020Bioengineering