Author

E. L. Brown

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2 Biophysics· 1 Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Assay:imaging· 4 Research Focus:cell type annotation· 3 Organism:mouse· 3 Research Focus:clustering· 2 Approach:deep learning· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:benchmarking· 1

Frequent Co-Authors

S. E. Bohndiek· 4 shared L. Hacker· 3 shared P. W. Sweeney· 3 shared T. L. Lefebvre· 3 shared J. Gröhl· 2 shared A. B. Popov· 1 shared A. G. Baker· 1 shared A. Vernet· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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4 shared papersBioengineering

S. E. Bohndiek

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Author profile →

5 papers

Recent·Most cited

In Vivo Monitoring of Cellular Senescence by Photoacoustic and Fluorescence Imaging Utilizing a Nanostructured Organic Probe

A. G. Baker, H.-L. Ou, M. Hartono, A. B. Popov, E. L. Brown, J. Joseph, M. Golinska, C. Sanghera, E. Gonzalez-Gualda, D. Macias, T. R. Else, H. F. Greer, A. Vernet, S. E. Bohndiek, L. Fruk, D. Munoz-Espin

This study develops a nanostructured organic probe, NanoJaggs, for in vivo monitoring of cellular senescence using photoacoustic and fluorescence imaging, showing specificity for chemotherapy-induced senescence in tumors.

bioRxiv · Jul 12, 2023 · PreprintCancer Biology

Unsupervised segmentation of 3D microvascular photoacoustic images using deep generative learning

P. W. Sweeney, L. Hacker, T. L. Lefebvre, E. L. Brown, J. Gröhl, S. E. Bohndiek

This paper introduces an unsupervised deep learning model for segmenting 3D vascular networks from photoacoustic images without requiring manual labels.

bioRxiv · Apr 30, 2023Biophysics

Performance evaluation of mesoscopic photoacoustic imaging

L. Hacker, E. L. Brown, T. L. Lefebvre, P. W. Sweeney, S. E. Bohndiek

This study evaluates the performance of a commercial photoacoustic mesoscopy system, showing high precision with low coefficients of variation but highlighting challenges in imaging vessel-like structures.

bioRxiv · Oct 17, 2022Bioengineering

Quantification of vascular networks in photoacoustic mesoscopy

E. L. Brown, T. L. Lefebvre, P. W. Sweeney, B. Stolz, J. Gröhl, L. Hacker, Z. Huang, H. Harrington, H. Byrne, S. E. Bohndiek

This paper develops a framework to quantify 3D vascular networks using mesoscopic photoacoustic imaging and evaluates segmentation methods for accuracy.

bioRxiv · Nov 22, 2021Bioengineering

Characterization of Peripheral Blood Mononuclear Cells Gene Expression Profiles of Pediatric Staphylococcus aureus Persistent and Non-Carriers Using a Targeted Assay

E. Israelsson, D. Chaussabel, R. S. Fischer, H. C. Moore, D. A. Robinson, H. T. Essigmann, E. L. Brown

The paper compares gene expression profiles of PBMCs from pediatric S. aureus carriers and non-carriers using a targeted assay, finding distinct innate immune responses to live vs. dead bacteria.

bioRxiv · Feb 8, 2019Immunology