Cell BiologybioRxivPreprint
Negative modulation of macroautophagy by HERPUD1 is counteracted by an increased ER-lysosomal network with impact in drug-induced stress cell survival
G. Vargas, O. H. Cortes, E. N. Arias-Munoz…·P. V. Burgos
The paper identifies HERPUD1 as a negative regulator of macroautophagy, showing that its stabilization promotes ER-lysosomal network expansion and enhances cell survival under stress.
DOI 10.1101/2021.06.14.447273