Integrative molecular roadmap for direct conversion of fibroblasts into myocytes and myogenic progenitor cells
I. Kim, A. Ghosh, N. Bundschuh, L. Hinte, F. von Meyenn, O. Bar-Nur
This study identifies distinct molecular trajectories in fibroblast reprogramming to myogenic progenitor cells versus myogenic transdifferentiation, highlighting Notch pathway activation as critical for iMPC formation.
bioRxiv · Aug 20, 2021Cell Biology