Kinesin-binding protein remodels the kinesin motor to prevent microtubule-binding
A. L. Solon, Z. Tan, K. L. Schutt, L. Jepsen, S. E. Haynes, A. I. Nesvizhskii, D. Sept, J. Stumpff, R. Ohi, M. A. Cianfrocco
This study determines the structural mechanism by which KIFBP remodels kinesin motors to block microtubule-binding, revealing a 2-pronged inhibition strategy.
bioRxiv · Jun 2, 2021Cell Biology