miR-100 and miR-125b Contribute to Enhanced 3D Growth and Invasiveness and can be Functionally Transferred to Silence Target Genes in Recipient Cells
H. M. Nelson, S. Qu, L. Huang, M. Shameer, K. C. Corn, S. N. Chapman, N. L. Luthcke, S. A. Schuster, L. A. Turnbull, L. L. Guy, X. Liu, K. C. Vickers, Q. Liu, J. L. Franklin, A. Weaver, , J. G. Patton
This study identifies miR-100 and miR-125b as regulators of 3D growth and invasiveness in cancer cells, showing they can be transferred extracellularly to silence target genes in recipient cells.
bioRxiv · Jan 16, 2024 · PreprintCancer Biology