Author

K. C. Vickers

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Bioengineering· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

D. L. Michell· 2 shared A. Faust· 1 shared A. G. Sorets· 1 shared A. M. Weaver· 1 shared A. S. Major· 1 shared A. Weaver· 1 shared B. Barman· 1 shared B. D. Appleton· 1 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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2 shared papersBioengineering

D. L. Michell

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

miR-100 and miR-125b Contribute to Enhanced 3D Growth and Invasiveness and can be Functionally Transferred to Silence Target Genes in Recipient Cells

H. M. Nelson, S. Qu, L. Huang, M. Shameer, K. C. Corn, S. N. Chapman, N. L. Luthcke, S. A. Schuster, L. A. Turnbull, L. L. Guy, X. Liu, K. C. Vickers, Q. Liu, J. L. Franklin, A. Weaver, , J. G. Patton

This study identifies miR-100 and miR-125b as regulators of 3D growth and invasiveness in cancer cells, showing they can be transferred extracellularly to silence target genes in recipient cells.

bioRxiv · Jan 16, 2024 · PreprintCancer Biology

Culture conditions greatly impact the levels of vesicular and extravesicular Ago2 and RNA in extracellular vesicle preparations.

L. Jimenez, B. Barman, Y. J. Jung, L. N. Cocozza, E. Krystofiak, C. E. Saffold, K. C. Vickers, J. T. Wilson, T. R. Dawson, A. M. Weaver

The paper investigates how culture conditions affect the levels of Ago2 and RNA in extracellular vesicles, finding that serum and cell state influence their presence.

bioRxiv · Jun 21, 2023Cancer Biology

Albumin-binding RNAi Conjugate for Carrier Free Treatment of Arthritis

J. M. Colazo, E. N. Hoogenboezem, M. C. Keech, N. Francini, V. Shah, F. Yu, J. H. Lo, A. G. Sorets, J. T. McCune, H. Cho, C. R. DeJulius, D. L. Michell, T. Maerz, K. C. Vickers, K. N. Gibson-Corley, , C. L. Duvall

This paper develops an MMP13-targeting siRNA conjugate that preferentially accumulates in arthritic joints, reducing disease markers and outperforming current treatments.

bioRxiv · May 31, 2023 · PreprintBioengineering

Inhibition of miR-22-3p reduces kidney disease associated with systemic lupus erythematosus

D. L. Michell, A. Faust, J. L. Moore, B. D. Appleton, M. Ormseth, M. Ramirez-Solano, Q. Sheng, J. F. Solus, C. M. Stein, K. C. Vickers, A. S. Major

This study shows that inhibiting miR-22-3p reduces lymphocyte accumulation and kidney disease in a mouse model of systemic lupus erythematosus.

bioRxiv · Jan 7, 2019 · PreprintImmunology