In situ reprogramming of gut bacteria by oral delivery
B. B. Hsu, I. N. Plant, L. Lyon, F. M. Anastassacos, J. C. Way, P. A. Silver
This study demonstrates the oral delivery of an engineered phage to reprogram gut bacteria in situ by targeting gene expression without disrupting the microbiota.
bioRxiv · Apr 15, 2020Bioengineering