Dormant spores sense amino acids through the B subunits of their germination receptors
L. Artzi, A. Alon, K. P. Brock, A. G. Green, A. Tam, F. H. Ramirez-Guadiana, D. Marks, A. Kruse, D. Z. Rudner
The paper identifies GerAB as the L-alanine sensor in spores, showing mutations in its ligand-binding pocket impair germination and substitutions enable response to other amino acids.
bioRxiv · Oct 28, 2021Microbiology