Author

L. Maes

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Cancer Biology· 1 Ecology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:mouse· 5 Research Focus:host-pathogen & immune response· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2

Frequent Co-Authors

G. Caljon· 4 shared S. Hendrickx· 3 shared H. Leirs· 2 shared L. Van Bockstal· 2 shared M. Pareyn· 2 shared N. Girma· 2 shared A. Kochora· 1 shared B. Caljon· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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4 shared papersMicrobiology

G. Caljon

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Long-term hematopoietic stem cells trigger quiescence in Leishmania parasites

L. Dirkx, S. Van Acker, Y. Nicolaes, J. L. R. Cunha, R. Ahmad, B. Caljon, H. Imamura, D. G. Ebo, D. Jeffares, Y. G.-J. Sterckx, L. Maes, S. Hendrickx, G. Caljon

This study shows that Leishmania parasites enter quiescence after 4-6 divisions in hematopoietic stem cells, enabling drug resistance and increased infectivity.

bioRxiv · Aug 23, 2023 · PreprintMicrobiology

Investigating the Role of Chromatin Remodeler FOXA1 in Ferroptotic Cell Death

E. Logie, L. Maes, J. Van Meenen, P. H. De Rijk, M. Strazisar, G. Joris, B. Cuypers, K. Laukens, W. V. Berghe

This study investigates the role of FOXA1 in ferroptotic cell death in multiple myeloma cells, finding that FOXA1 is upregulated and binds to pericentromeric regions during ferroptosis.

bioRxiv · Oct 13, 2021 · PreprintCancer Biology

Miltefosine enhances infectivity of miltefosine-resistant Leishmania infantum by attenuating innate immune recognition

D. Bulte, L. Van Bockstal, L. W. Dirkx, M. Van den Kerkhof, C. De Trez, J.-P. Timmermans, S. Hendrickx, L. Maes, G. Caljon

This study shows that miltefosine-resistant Leishmania infantum parasites have reduced in vivo fitness but gain infectivity when exposed to miltefosine, due to suppressed innate immune activation.

bioRxiv · Feb 22, 2021Microbiology

Evaluation of a pan-Leishmania SL-RNA qPCR assay for parasite detection in laboratory-reared and field-collected sand flies and reservoir hosts.

M. Pareyn, R. Hendrickx, N. Girma, S. Hendrickx, L. Van Bockstal, N. Van Houtte, S. Shibru, L. Maes, H. Leirs, G. Caljon

This study evaluates a pan-Leishmania SL-RNA qPCR assay for detecting Leishmania in sand flies and hyrax tissue samples, showing it is as effective as kDNA assays and can detect low parasite equivalents.

bioRxiv · Jan 8, 2020Microbiology

Feeding behavior and activity of Phlebotomus pedifer and potential reservoir hosts of Leishmania aethiopica in southwestern Ethiopia.

M. Pareyn, A. Kochora, L. Van Rooy, N. Eligo, B. Vanden Broecke, N. Girma, B. Merdekios, T. Wegayehu, L. Maes, G. Caljon, B. Lindtjorn, H. Leirs, F. Massebo

This study investigates the feeding behavior and activity of Phlebotomus pedifer sand flies and their role in Leishmania aethiopica transmission in Ethiopia, finding humans are the main blood source and livestock likely do not contribute to transmission.

bioRxiv · Nov 26, 2019Ecology