MicrobiologybioRxiv
Miltefosine enhances infectivity of miltefosine-resistant Leishmania infantum by attenuating innate immune recognition
D. Bulte, L. Van Bockstal, L. W. Dirkx…·G. Caljon
This study shows that miltefosine-resistant Leishmania infantum parasites have reduced in vivo fitness but gain infectivity when exposed to miltefosine, due to suppressed innate immune activation.
DOI 10.1371/journal.pntd.0009622