Author

L. Milles

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 1 Approach:experimental assay· 1 Research Focus:protein design· 1 Assay:protein sequence· 1

Frequent Co-Authors

D. Baker· 1 shared D. Tischer· 1 shared H. E. Gaub· 1 shared I. K. Anishchenko· 1 shared J. Wang· 1 shared R. Dong· 1 shared S. Lisanza· 1 shared S. Ovchinnikov· 1 shared

Activity by Year

2019-2020 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 21 mutual co-author links

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1 shared paperBiochemistry

D. Baker

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2 papers

Recent·Most cited

Design of proteins presenting discontinuous functional sites using deep learning

D. Tischer, S. Lisanza, J. Wang, R. Dong, I. K. Anishchenko, L. Milles, S. Ovchinnikov, D. Baker

This paper designs proteins with discontinuous functional sites using deep learning, eliminating the need for pre-defined secondary structures and enabling diverse scaffold generation.

bioRxiv · Nov 29, 2020 · PreprintBiochemistry

Is mechanical receptor ligand dissociation driven by unfolding or unbinding?

L. Milles, H. E. Gaub

The paper investigates whether mechanical dissociation of protein-protein interactions involves unfolding or unbinding, finding that one or both partners can unfold during dissociation.

bioRxiv · Apr 2, 2019 · PreprintBiophysics