Cryo-EM structure of the calcium release-activated calcium channel Orai in an open conformation
X. Hou, I. R. Outhwaite, L. Pedi, S. B. Long
The paper presents a cryo-EM structure of the Orai channel in an open conformation, revealing the mechanism of channel opening and its role in Ca2+ entry regulation.
bioRxiv · Sep 3, 2020Biochemistry