Conformational dynamics and target-dependent myristoyl switch of calcineurin B homologous protein 3
F. Becker, S. Fuchs, L. Refisch, F. Drepper, W. Bildl, U. Schulte, S. Liang, J. I. Heinicke, S. C. Hansen, C. Kreutz, B. Warscheid, B. Fakler, E. V. Mymrikov, C. Hunte
This study investigates the conformational dynamics and target-dependent myristoyl switch of CHP3, revealing that Ca2+ binding and myristoylation independently regulate its function and membrane association.
bioRxiv · Sep 23, 2022Biochemistry