Single Cell Analysis of Regions of Interest (SCARI) using a novel photoswitchable tag
A. M. van der Leun, M. E. Hoekstra, L. Reinalda, C. L. Scheele, M. Toebes, M. J. van de Graaff, H. Li, A. Bercovich, Y. Lubling, E. David, D. S. Thommen, A. Tanay, J. van Rheenen, I. Amit, S. I. van Kasteren, T. N. Schumacher
The paper introduces a photoswitchable tag technology to isolate and analyze live cells from specific regions in complex tissues, enabling spatially defined single-cell RNA sequencing.
bioRxiv · Oct 2, 2020 · PreprintBioengineering