Author

C. L. Scheele

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Bioengineering· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 4 Approach:experimental assay· 4 Research Focus:cell signaling & trafficking· 3 Organism:human· 3 Research Focus:development & morphogenesis· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

J. van Rheenen· 2 shared L. Mourao· 2 shared A. Bercovich· 1 shared A. Bruna· 1 shared A. De Jaime-Soguero· 1 shared A. Isomursu· 1 shared A. Laiho· 1 shared A. M. van der Leun· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersCell Biology

J. van Rheenen

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Chemotherapy-treated breast cancer cells activate the Wnt signaling pathway to enter a diapause-DTP state.

F. Lluis, Y. Ellaithy, W. A. Abreu de Oliveira, A. Pabba, A. Qualizza, F. Richard, P. Athanasouli, C. R. Luci, W. De Wispelaere, L. Mourao, S. Hamer, S. Moens, A. De Jaime-Soguero, M. Francesca Baietti, S. J. Hutten, , D. Annibali

This study shows chemotherapy induces a Wnt-active diapause-DTP state in breast cancer cells, which can be targeted by combined Wnt and chemotherapy inhibition.

bioRxiv · Mar 8, 2024 · PreprintCancer Biology

Filopodia-mediated basement membrane assembly at pre-invasive tumor boundaries

E. Peuhu, G. Jacquemet, C. L. Scheele, A. Isomursu, I. Paatero, K. Thol, M. Georgiadou, C. Guzman, S. Koskinen, A. Laiho, L. L. Elo, P. Boström, P. Hartiala, J. van Rheenen, J. Ivaska

This study shows MYO10 promotes BM assembly in DCIS to limit invasion but facilitates cancer cell dissemination in invasive breast cancer.

bioRxiv · Oct 22, 2021 · PreprintCell Biology

Annexin A1 is a polarity cue that directs planar mitotic spindle orientation during mammalian epithelial morphogenesis

M. Fankhaenel, F. S. Golestan Hashemi, L. Mourao, E. Lucas, M. M. Hosawi, P. Skipp, X. Morin, C. L. Scheele, S. Elias

This study identifies Annexin A1 as a polarity cue that directs planar mitotic spindle orientation in mammalian epithelial cells by regulating LGN and NuMA cortical anchoring.

bioRxiv · Jul 28, 2021 · PreprintCell Biology

Single Cell Analysis of Regions of Interest (SCARI) using a novel photoswitchable tag

A. M. van der Leun, M. E. Hoekstra, L. Reinalda, C. L. Scheele, M. Toebes, M. J. van de Graaff, H. Li, A. Bercovich, Y. Lubling, E. David, D. S. Thommen, A. Tanay, J. van Rheenen, I. Amit, S. I. van Kasteren, T. N. Schumacher

The paper introduces a photoswitchable tag technology to isolate and analyze live cells from specific regions in complex tissues, enabling spatially defined single-cell RNA sequencing.

bioRxiv · Oct 2, 2020 · PreprintBioengineering