Cancer BiologybioRxivPreprint
More than a ligand: PD-L1 promotes oncolytic virus infection via a metabolic shift that inhibits the type I interferon pathway.
J. Hodgins, J. Abou-Hamad, A. Hagerman…·M. Ardolino
PD-L1 promotes oncolytic virus infection by inhibiting the type I interferon pathway through a metabolic shift involving enhanced glycolysis and lactate production.
DOI 10.1101/2022.08.31.506095