L. Sacconi

The paper demonstrates that cardiac myocyte T-tubules can generate action potentials autonomously, distinct from those in the sarcolemma, using an all-optical method.

The paper develops a 3D-printed targeted sampling method to accurately identify and study arrhythmogenic sites in the mammalian heart after myocardial infarction.

This study uses 3D imaging to analyze capillary network remodeling in spontaneously hypertensive rats, finding increased density and dispersion before hypertension onset.

This paper introduces a new imaging method to map voltage activity in whole zebrafish hearts at KHz rates, revealing novel electrical propagation dynamics in the atrioventricular canal.

RAPID provides real-time autofocus for wide-field microscopy, enabling high-quality imaging and 3D tracking of fast-moving organisms.