Helminth infection driven gastrointestinal hypermotility is independent of eosinophils and mediated by alterations in smooth muscle instead of enteric neurons
N. Harris, K. Barry, G. Coakley, M. Moyat, C. Daunt, A. Zaini, L. Wickramasinghe, B. Yumnam, M. Camberis, G. Le Gros, O. Perdijk, J. Foong, J. Bornstein, B. Marsland
This study shows that helminth-induced intestinal hypermotility in mice is driven by smooth muscle changes, not eosinophils or the enteric nervous system.
bioRxiv · Oct 23, 2023Immunology