Author

L. X. Phan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 3

Signature Assays, Organisms & Methods

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Approach:mechanistic / dynamical model· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Assay:cryo-EM· 1 Approach:deep learning· 1 Organism:human· 1 Assay:multiome· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

J. Crain· 3 shared M. Sansom· 3 shared S. J. Tucker· 3 shared A. P. Owji· 1 shared C. I. Lynch· 1 shared H. Martinez-Seara· 1 shared T. Yang· 1 shared V. C. Chamorro· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 20 mutual co-author links

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3 shared papersBiophysics

J. Crain

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Electronic Polarizability Tunes the Function of the Human Bestrophin 1 Cl- Channel

L. X. Phan, A. P. Owji, T. Yang, J. Crain, M. Sansom, S. J. Tucker

The paper shows that electronic polarization is essential for accurately simulating Cl- permeation through the hBest1 channel and resolving ion-like densities in cryo-EM structures.

Journal of Chemical Theory and Computation · Jan 3, 2025Peer-reviewedBiophysics

Influence of Electronic Polarization on the Binding of Anions to a Chloride-Pumping Rhodopsin

L. X. Phan, V. C. Chamorro, H. Martinez-Seara, J. Crain, M. Sansom, S. J. Tucker

This study investigates how electronic polarization affects chloride ion binding to a chloride-pumping rhodopsin using molecular dynamics simulations with different force fields.

Biophysical Journal · Apr 1, 2023Peer-reviewedBiophysics

Influence of effective polarization on ion and water interactions within a biomimetic nanopore

L. X. Phan, C. I. Lynch, J. Crain, M. Sansom, S. J. Tucker

This study investigates ion and water interactions in a biomimetic nanopore using MD simulations with and without polarization effects, finding that polarization significantly influences ion behavior at hydrophobic interfaces.

bioRxiv · Dec 10, 2021Biophysics