Redox regulation of the SARS-CoV-2 main protease provides new opportunities for drug design
K. Tittmann, L.-M. Funk, G. Poschmann, A. Chari, F. Rabe von Pappenheim, K. M. Stegmann, A. Dickmanns, N. Eulig, M. Wensien, E. Paknia, G. Heyne, E. Penka, A. R. Pearson, C. Berndt, T. Fritz, , U. Curth
This study identifies redox regulation of SARS-CoV-2 Mpro and discovers antiviral reagents that mimic redox switching, suggesting new drug targets.
bioRxiv · Apr 18, 2022 · PreprintBiochemistry