Author

A. Chari

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Biophysics· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:protein structure prediction· 2 Assay:bulk RNA-seq· 1 Research Focus:clustering· 1 Assay:cryo-EM· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1

Frequent Co-Authors

E. Paknia· 2 shared A. Dickmanns· 1 shared A. Lagana· 1 shared A. R. Pearson· 1 shared C. Berndt· 1 shared D. Madduri· 1 shared D. T. Melnekoff· 1 shared E. Penka· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersBiochemistry

E. Paknia

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Redox regulation of the SARS-CoV-2 main protease provides new opportunities for drug design

K. Tittmann, L.-M. Funk, G. Poschmann, A. Chari, F. Rabe von Pappenheim, K. M. Stegmann, A. Dickmanns, N. Eulig, M. Wensien, E. Paknia, G. Heyne, E. Penka, A. R. Pearson, C. Berndt, T. Fritz, , U. Curth

This study identifies redox regulation of SARS-CoV-2 Mpro and discovers antiviral reagents that mimic redox switching, suggesting new drug targets.

bioRxiv · Apr 18, 2022 · PreprintBiochemistry

Patient Similarity Network of Multiple Myeloma Identifies Patient Sub-groups with Distinct Genetic and Clinical Features

S. Bhalla, D. T. Melnekoff, J. Keats, K. Onel, D. Madduri, J. Richter, S. Richard, A. Chari, H. J. Cho, J. T. Dudley, S. Jagannath, A. Lagana, S. Parekh

The paper introduces MM-PSN, a multi-omics patient similarity network for Multiple Myeloma, identifying three broad groups and twelve sub-groups with distinct genetic and clinical features.

bioRxiv · Jun 2, 2020 · PreprintCancer Biology

Breaking the next Cryo-EM resolution barrier - Atomic resolution determination of proteins!

K. M. Yip, N. Fischer, E. Paknia, A. Chari, H. Stark

This paper reports a 1.25 Å resolution cryo-EM structure of apoferritin, achieving atomic-level detail and improving density map quality for drug design.

bioRxiv · May 21, 2020 · PreprintBiophysics