Cell BiologyiSciencePeer-reviewed
Huntingtin polyglutamine expansions misdirect axonal transport by perturbing motor and adaptor recruitment
Emily N. P. Prowse, Brooke A. Turkalj, Muriel Sébastien…·Adam G. Hendricks
This study shows that HTT polyQ expansions disrupt motor and adaptor recruitment to vesicles, causing transport defects and altered responses to neuroinflammatory stress.
2 citations