Rapid dexamethasone treatment inhibits LPS-induced cytokine storm in mice
Fen Zhang, Lanlan Xiao, Yujia Li, Rilu Feng, Menghao Zhou, Shima Tang, Roman Liebe, Matthias Ebert, Steven Dooley, Lanjuan Li, Honglei Weng
This study shows that rapid dexamethasone treatment inhibits LPS-induced cytokine storm in mice by blocking RNA Pol II activity in pre-loaded pro-inflammatory genes.
bioRxiv · Dec 7, 2023 · PreprintMolecular Biology