Matthias Ebert

The paper identifies a YB-1-mA-DNMT regulatory axis that drives cisplatin resistance in iCCA by promoting ABCB1 expression through promoter demethylation.

The paper uses a patient-derived rectal cancer organoid platform to identify MEK and PARP inhibitors that synergize with radiation to enhance treatment response in locally advanced rectal cancer.

This study shows ECM1 prevents hepatic fibrosis by inhibiting TGF-β1 activation, with implications for developing safe anti-fibrotic therapies.

This study shows that rapid dexamethasone treatment inhibits LPS-induced cytokine storm in mice by blocking RNA Pol II activity in pre-loaded pro-inflammatory genes.